Cognitive And Psychoemotional Disorders In Hypothyroidism And The Possibilities Of Cognitive-Behavioral Therapy
Published: 2026-01-10 · Issue: 2026 · Volume 1 · Issue 1
Abstract
Hypothyroidism is one of the most common endocrine diseases after diabetes mellitus and is characterized not only by somatic manifestations but also by cognitive and psycho-emotional disorders. A study conducted at the Khorezm Regional Endocrinology Dispensary with the participation of 104 women of reproductive age revealed a high prevalence of cognitive impairments (68%) and psycho-emotional disorders (54%), including depression, anxiety, and aggressiveness. An inverse correlation was found between TSH levels and cognitive functions (r = -0.41; p<0.05). The use of cognitive-behavioral therapy (CBT) significantly reduced the severity of depression and anxiety, improved memory and attention indicators, and enhanced patients’ quality of life. Adapted CBT demonstrated greater effectiveness compared to the standard method. Economic analysis showed that the average length of hospitalization decreased by 4.5 days and the cost of treatment per patient was reduced by 2.85 million UZS. The results of the study confirm that integrating CBT into the standard treatment of hypothyroidism is both clinically and economically justified.
Keywords
hypothyroidism, cognitive disorders, psycho-emotional disorders, cognitive-behavioral psychotherapy