The Axiom of the New Scientific Era

Journal of Science and Innovation

Clinical Significance of Mucociliar Transport Disorders in Polypotic Rhinosinusitis

Avezov Mukhiddin Ikramovich

Published: 2026-04-12 · Issue: 2026 · Volume 1 · Issue 2

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Abstract

This article is devoted to the clinical significance of impaired mucociliary transport function of the nasal mucosa in polypoid rhinosinusitis. Polypoid rhinosinusitis is a common, recurrent, and multifactorial chronic inflammatory disease, in the course and severity of which the functional state of the nasal mucosa plays an important role. One of the goals of the dissertation is to assess the course and recurrence of polypoid rhinosinusitis by determining the mucociliary clearance of the nasal cavity, and also in the scientific novelty part, it is shown that a decrease in the mucociliary transport function of the nasal mucosa in patients with polypoid rhinosinusitis worsens the course of the disease. The article analyzes the physiological basis of mucociliary transport, its role in the pathogenesis of polypoid rhinosinusitis, its relationship with the clinical manifestations of the disease, and its significance in the diagnosis and selection of treatment tactics. It is substantiated that impaired mucociliary transport is associated with impaired nasal breathing, stabilization of mucous secretions, prolonged preservation of the inflammatory process, and an increased risk of recurrence. It was concluded that the study of mucociliary clearance in the comprehensive assessment of polypoid rhinosinusitis is an important criterion for predicting the clinical course, monitoring the effectiveness of treatment, and assessing the risk of recurrence.

Keywords

polypoid rhinosinusitis, mucociliary transport, mucociliary clearance, nasal mucosa, functional disorders, recurrence, diagnosis.